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In March 2024, FDA approved a new indication to reduce MACE in adults with established CV disease and overweight/obesity based on SELECT, marking the first obesity medication with a dedicated CV riskreduction label in this population

As a result, ferroptosis of cardiomyocytes was inhibited, I/R-induced cardiac injury was reduced, and cardiac function was enhanced [109]

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Vida media plasmtica de TB-500: Aproximadamente 2-3 horas debido a su mayor tamao molecular (~4963 g/mol) y aclaramiento ms lento