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Note: Participants in the STEP-1 trial were patients with obesity

(PubMed) Clarke JD, Riedl K, Bella D, Schwartz SJ, Stevens JF, Ho E

For Ozempic, nausea occurs in approximately 20% of patients, while Wegovy has higher rates of gastrointestinal effects, with nausea occurring in up to 44% of patients (dose-dependent)

Uchakina, O.N., Uchakin, P.N., Myadyants, M.G., Andrianova, M.A., Ochkur, A.V., & Afanas'ev, V.V

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Similarly, endeavors in clinical research to mend the BBB through attenuation of brain inflammation or the targeting of cerebral A in AD patients have, to date, proven unsuccessful [307]