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UpToDate (updated as of 2025).

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For a 90 kg (198 lb) man, thats approximately 2,250 nmol total, which converts to roughly 190210 mcg per dose depending on the exact molecular calculations

For optimal GH response: Morning (fasted): Mimics natural morning GH surge Post-workout: Enhances recovery and IGF-1 response Before bed: Aligns with deep sleep GH release Avoid taking it immediately after meals, as insulin blunts GH secretion

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Available: /pmc/articles/PMC3609680/ [6] Dr COURTNEY CRAIG Diet & Nutrition for Chronic Fatigue & Fibromyalgia. Accessed: Nov