Mol Med Rep 16:12691277 Lai SW, Chen JH, Lin H et al (2018) Regulatory Effects of neuroinflammatory responses through brain-derived neurotrophic factor signaling in Microglial cells
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[5] Even when fiber intake is adequate, several factors can impair butyrate production: [6] Microbiome disruption from antibiotics, stress, or illness Age-related decline in butyrate-producing bacteria Rapid transit time limiting fermentation Individual variation in bacterial composition Competition from other bacterial metabolic pathways This production variability explains why some people experience dramatic benefits from increasing fiber intake while others see little change despite their best efforts
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mL -1 was then added and 3 to 4 h hours later, the medium was aspirated, and the formazan product was solubilized by the addition of a ethanol/DMSO (1:1) solution