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Youth-onset type 2 diabetes progresses faster, is harder to control, and carries earlier and more severe complications, making early intervention critical

10.1177/2047487317728765 98 MarzoliniS.BlanchardC.AlterD

GH has several effects on the body, including a glucose-sparing effect, meaning that instead of the body utilizing glucose as a primary energy source, the body taps into adipose tissue, using stored fat as energy

Despite this, there are instances where the ability to synthesize GSH, and in turn establish an adaptive response is compromised

Multiple animal studies demonstrate significantly accelerated healing of Achilles tendon, rotator cuff, and medial collateral ligament injuries

Interestingly, this effect was mediated by the release of CCK and GLP-1 and subsequent activation of their receptors, possibly on VANs (see Hormonal gut-brain signaling section)