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Q12: What labs or monitoring do you recommend

She had lost a total of 30 pounds, and her A1C level had improved further to 6.8%

6,14 Furthermore, GLP-1 signaling indirectly enhances and restores the insulin signaling pathway in neurons, leading to a reduction in the phosphorylation of insulin receptor substrates and the burden caused by monomeric -synuclein

Adding retatrutide on top makes it worse

Survodutide Dosing The SYNCHRONIZE Phase 3 trials use a modified escalation protocol designed to improve tolerability compared to Phase 2: Starting dose: Low dose with gradual increases Escalation: Extended titration period with flexibility Target doses: 3.6mg or 6.0mg weekly (SYNCHRONIZE-1) Pause option: Ability to temporarily stop dosing for GI symptoms Time to maintenance: Extended to reduce side effects The inclusion of a pause option in Survodutide trials reflects lessons learned from Phase 2 about the importance of allowing patient-directed tolerance management

But in the long run, its usually better to put your money toward options that are clinically proven and safe, rather than products that rely on marketing rather than evidence