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Introduction Rheumatoid Arthritis (RA) is a chronic immune-mediated inflammatory disorder that involves the synovial membranes of multiple joints (Sewell and Trentham, 1993

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The effects on glucagon secretion are profound at both 3.5 and 12 mmol/l glucose, indicating that endogenous somatostatin is secreted and exerts paracrine effects at both low and high glucose, although somatostatin secretion is dependent on the prevailing glucose levels

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