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158 A separate 12-week crossover study in 29 postmenopausal women randomized to receive 3.3 grams daily of maca or placebo, each for six weeks, found maca reduced symptoms of depression relative to placebo

Ann Neurol 1989;26:456

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They also appear to reduce food-related responses in the brain, quieting the constant food noise that can drive cravings

[1] [28] [123] Other potential physical side effects include appetite loss, blurred vision, dry mouth, excessive grinding of the teeth, nosebleed, profuse sweating, rhinitis medicamentosa (drug-induced nasal congestion), reduced seizure threshold, tics (a type of movement disorder), and weight loss