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It is characterized by ROS-induced dissociation of the oxygen-sensitive kinase KEAP1, activating the NRF2 signaling pathway and caspase-8-dependent cell death [241, 242]

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These results should help to influence health policy in Portugal and similar countries where GLP-1 receptor agonist and SGLT-2 inhibitor use is limited, despite their demonstrated efficacy [8, 46, 47]

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Most patients begin noticing improvements in recovery and inflammation within the first few weeks of a supervised protocol

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