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Brain tissue homogenates and serum samples were collected to quantify intestinal permeability markers (zonulin and occluding), oxidative-stress markers (GSH, MDA, CAT), and GABA-receptor gene expression using ELISA and biochemical assays

Most patients report that they see or feel different in the first 8 weeks of starting semaglutide with some saying they can even see a difference after 4 weeks of use

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