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The honest answer is that the mechanism of DSIP is not fully understood

Topical medications are the first-line therapy and include prostaglandin analogues, -blockers, -agonists, carbonic anhydrase inhibitors, and Rho-kinase inhibitors, each with distinct mechanisms and side-effect profiles [12,13,14]

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Subsequently, 50 L of the probe payload solution was added dropwise to the vesicle suspension at room temperature while vortexing, with no precipitation observed

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