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The first experimental IUSCT success employed transplacental injection of adult allogeneic BM haematopoietic cells at E11, into c-kit deficient mouse fetuses, which reversed the genetic anemia produced by the c-kit defect

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Malabsorption Issues: This is the most prevalent reason for B12 deficiency, even for those with B12-rich diets

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doi: 10.1016/j.cellimm.2016.07.007