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Synergy is inferred from the individual mechanisms, not demonstrated in combination: GHK-Cu: Cosmetically Focused Clinical Data Split-face human dermatology trials on wrinkle depth and skin density (n usually under 50 per arm) Microarray gene mapping (4,000+ genes)

Speight J, Holmes-Truscott E

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This approach is hypothesized to help alleviate the differences in dielectric properties within heterogeneous tissue (132) while ensuring saturated cell permeabilization (124)

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