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Desde aqu la informacin es transmitida al hipotlamo y a otras regiones del cerebro (13)

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Fatigue is listed as a common adverse reaction (occurring in 5% of patients) in the FDA prescribing information for both Wegovy (semaglutide 2.4 mg) and Zepbound (tirzepatide), and occurred more frequently than with placebo in clinical trials

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Left, in the inactive conformation, the top of the transmembrane domain is stabilized by interactions of the ECD with the TM6ECL3TM7 region

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