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When to Speak to a Healthcare Professional Flatulence is usually harmless, but you should reach out to your pharmacist or GP if: Gas is severe, pain ful, or affecting your daily life You also have persistent diarrhoea or constipation Youve had recent unexplained weight loss You feel pressure, cramping, or bloating that doesnt improve They can check for other causes and recommend appropriate support, whether thats adjusting your dose, checking for intolerances, or suggesting over-the-counter remedies

The risk of lactic acidosis with Metformin is negligible in children and adolescents on Metformin in obesity (129, 131)

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Semaglutides Impact on Weight Loss Clinical Trials and Research Findings Clinical trials have consistently demonstrated Semaglutides efficacy in promoting weight loss