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This is because the entire dose is injected directly into the bloodstream, and therefore bypasses the factors listed above (e.g
What's the unopened shelf life of a sealed vial
This is a common myth
Once reconstituted, aliquot into single-use volumes and store at -20C under standard laboratory conditions to maintain experimental consistency
DAMGO-induced MOR internalization in striatal neurons is impaired by over-expression of a dominant negative mutant of arrestin 2 corresponding to the last 100 amino acids (arrestin 2 319418) (Haberstock-Debic et al., 2005)
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