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When estrogens growth signals are strongand progesterones calming effect is weaker than expected (often described as progesterone resistance)the endometrium can behave in a more persistently inflamed, reactive way

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For the sub-chronic treatment, mice received a daily intraperitoneal injection of either 0.2 mg/kg liraglutide (Tocris) or vehicle (PBS) 30 minutes before lights out for 14 days