this is something seen with other incretin therapies as well
[18] [19] Appetite regulation mechanisms: GLP-1 receptors in the hypothalamus and brainstem mediate satiety signaling
Buckley ST, Bkdal TA, Vegge A, Maarbjerg SJ, Pyke C, Ahnfelt-Rnne J, et al
How Pills Compare To Injections Today (Efficacy, Tolerability, Access) When considering a GLP-1 medication, the big question for many is whether a pill can truly deliver the same results as an injection
Lixisenatide is a 44 amino acid synthetic peptide derivative of exendin-4 [ Figure 2 , Table 1 ]
And here is the important part: if you miss two or more consecutive doses, you may need to restart the full titration schedule from 0.25 mg to avoid severe gastrointestinal side effects