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Even modest weight reductions of 5-10% can restore normal menstrual function in some women with insulin resistance or PCOS, according to reproductive endocrinology research

doi: 10.1016/j.bbi.2021.07.009 19 ZhuSHuXFanY

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Weickert CS, Fung SJ, Catts VS, Schofield PR, Allen KM, Moore LT, et al

The absence of reproductive toxicity data is the single largest knowledge gap