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Priority research needs include large-scale randomized controlled trials to establish efficacy and safety, dose-ranging studies to optimize treatment protocols, long-term safety studies particularly regarding cancer risk, and comparative effectiveness research with established therapies
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There is no quality guarantee, and dosing errors with injectable compounds can be dangerous
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Taking into consideration the recently described NPPC population (which shows stem cell characteristics) in healthy and degenerated IVDs, it is tempting to hypothesize that NPPCs may be in cross-talk with resident NCs and have a functional role in the differentiation and maintenance of NCs
High intensity interval training protects from Post Traumatic Stress Disorder induced cognitive impairment
