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Notably, in erythroid cells, caspase-3 activation does not guarantee apoptosis execution, since the transcriptional factor GATA-1 essential for erythropoiesis is protected from caspase-3 by HSP70 (heat shock protein 70)

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5.2 Neurotoxic mechanisms 5.2.1 Neuroinflammation Ketamine-induced neurotoxicity is associated with neuroinflammation

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rather, dietary supplements that typically range from 50 to 600 mg are the primary sources of LA, and most information as to its bioavailability comes from studies using supplements. 20 For these reasons, the Save Institute recommends taking a daily supplement of at least 100 mg of alpha lipoic acid, and specifically a stabilized R-ALA

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