There's even a 6-year human study from Russia where elderly subjects on epithalamin had lower cardiovascular mortality and better immune function than controls
In 2012 and 2017, Shimu passed GMP inspection routinely by China Ministry of Agriculture

Apply an appropriate amount to cleansed (and toned) skin Pat into the skin until fully absorbed Use in the morning and at night Water,Centella Asiatica Extract 22.7%,Glycerin,Cetyl Ethylhexanoate,Butylene Glycol,Polyglyceryl-3 Diisostearate,Niacinamide,Stearic Acid,Sodium Polyacryloyldimethyl Taurate,Silica,Sodium Hyaluronate,Glyceryl Stearate,Beeswax,Butyrospermum Parkii Butter,Macadamia Ternifolia Seed Oil,Hydrogenated Polydecene,Betaine,Glutathione,Trehalose,Adenosine,Citric Acid,Trideceth-10,Disodium EDTA,Sodium Citrate,Caprylic/Capric Triglyceride,Hydrogenated Lecithin,Cholesterol,Xanthan Gum,Nelumbo Nucifera Extract,Artemisia Annua Extract,Oryza Sativa Extract,Saccharomyces Ferment,Solanum Melongena Fruit Extract,Melaleuca Alternifolia Leaf Extract,Hydrolyzed Collagen,Squalane,Beta-Glucan,Dipropylene Glycol,Hippophae Rhamnoides Fruit Extract,Madecassic Acid,Asiaticoside,Asiatic Acid,Propanediol,Hydroxyacetophenone,1,2-Hexanediol,Ethylhexylglycerin,Dipotassium Glycyrrhizate *For the most recent ingredient list, please consult the product packaging or contact us for a product photo.

This finding laid the groundwork for decades of research (noted in the table below) exploring copper-peptide signaling and its potential biomedical and cosmetic applications
Mil Med 180: 748753, 2015 [DOI] [PubMed] [Google Scholar] 42.Parish RC, Todman S, and Jain SK
The molar excess of BCPB in relation to N-Hcy-Lys was 50:1