After the ARP intervention in HFD-induced male C57BL/6 mice for 12 weeks, the fatty acid pathway regulating lipogenesis was inhibited, the levels of antioxidant enzymes, such as GPX, glutathione S-transferase (GST) and SOD were increased, and MDA levels were decreased
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Another factor to consider is gastrointestinal tolerance
The storage lesion is exacerbated in some categories of donors as a function of biology (sex, age) 21 , genetic traits 22,23,24,25 , and lifestyle-associated exposures 26 (comprehensively reviewed in 15,21,27,28