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Metabolic studies showed that AOD9604-treated animals had increased lipolytic rates measured in isolated adipocytes, elevated circulating free fatty acid levels, and enhanced fatty acid oxidation rates
Studies suggest subcutaneous administration achieves 7085% bioavailability compared to oral routes, though oral protocols at 100150mg compensate for first-pass metabolism
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has observed that GH relevant adipose tissue in a depot-specific manner and relevant other features of adipose tissue (for example, senescence, adipocyte subpopulations, and fibrosis), all of which [may] relevant lipolysis