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72 Our team used palmitic acid stimulation to induce neuronal IR, confirming that ER stress is involved in the functional damage of neurons induced by IR, and exendin significantly alleviates both ER stress and neuronal damage (data not shown)

Van Dijck E, Beckers S, Diels S, et al

The mechanism argument first: semaglutide binds to and activates GLP-1 receptors

The other fragment, called DAG, stays in the membrane and helps switch on another enzyme family called protein kinase C (PKC), which adds phosphate groups to selected proteins and thereby changes their activity

Mitochondrial dysfunction in autism spectrum disorders

doi: 10.1007/s11695-020-05082-2