It will be usefull to better underdstand the best exit strategy from GLP1 RA and the physiopathology underlying the MOA during entry treatment phase also, respect physiology before treating the physiopatlogy trigger point, it is not a matter of AE and body weight gain may be consider an Expected AE
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Think about it: you have one drug (Jardiance) pushing sugar out through the kidneys, and another (a GLP-1) managing appetite and improving your body's insulin response
Wegovy HD 7.2mg dose average weight loss was ~21% at 72 weeks in adults with obesity in the STEP UP Trial (NCT05646706), in patients who stayed on treatment