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Food intake per mouse was calculated based on the amount of food consumed divided by time and the number of mice per cage

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[1] The substitutions (at positions 2, 8, 15, and 27) were selected to resist enzymatic degradation while preserving receptor binding affinity

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Design, synthesis and anti-diabetic activity of novel 1, 2, 3-triazole-5-carboximidamide derivatives as dipeptidyl peptidase-4 inhibitors