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Association of GLP-1 Receptor Agonists and Hepatocellular Carcinoma Incidence and Hepatic Decompensation in Patients With Type 2 Diabetes

10.1007/s00125-011-2317-z 67 SanyalA

doi: 10.1016/j.molmet.2021.101351 148 American Diabetes Association

In the trial of adult patients with an eGFR 30 to less than 60 mL/min/1.73 m2, 13 patients receiving dapagliflozin experienced bone fractures compared to none receiving placebo

The exact reason isnt fully understood, but the dose-dependent pattern across multiple medications suggests it may be related to how these drugs interact with nerve signaling at higher concentrations

For now you will only be able to get it privately, through pharmacies and regulated online clinics