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While both are powerful antioxidants that play crucial roles in protecting your cells from oxidative stress, they work in fundamentally different ways

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To prevent ROS production from semiquinones, the cytosolic, NRF2-regulated flavoproteins NAD(P)H: quinone oxidoreductases (NQOs) and aldo-keto reductase (AKR) can compete with P450 reductases and convert quinones to a relatively stable hydroquinones (quinols) [35]

In the presence of salicylamine, there were no significant changes in Vmax (Figure 5g) or Km (Figure 5h) when cells were treated with AA under non-oxidative or oxidative conditions with respect to the control condition