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doi: 10.1016/j.cell.2018.08.067 15

conducted clinical research and reported that MSU not only stimulates white blood cells to produce more LTB4 but also inhibits LTB4 metabolism, causing it to persist and recruit more neutrophils (75)

This method bypasses the digestive system, which means more of the peptide reaches the bloodstream and target tissues

doi: 10.3389/fphys.2024.1346173 Received 29 November 2023 Accepted 09 February 2024 Published 26 February 2024 Volume 15 - 2024 Edited by Mariano A

doi: 10.1093/stcltm/szac004 84 XiaoXXuMYuHWangLLiXRakJet al

Intestinal phospholipid disequilibrium initiates an ER stress response that drives goblet cell necroptosis and spontaneous colitis in mice