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doi: 10.1007/s11886-019-1208-7 14 GaoXCaoQChengYZhaoDWangZYangHet al

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Temperature changes can happen during transit, and what matters most is how the medication is handled after delivery and whether it stayed within acceptable conditions

Considerations include: Lower initial dosing where appropriate Close monitoring for gastrointestinal intolerance Assessment of comorbidities and polypharmacy risks 15.2 Administration to Pregnant Women Human data remain limited