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The JAMA real-world study comparing semaglutide and tirzepatide outcomes in clinical practice found that tirzepatide was associated with significantly greater weight loss than semaglutide, confirming that the clinical trial advantage holds outside of controlled environments

It is not recommended to use GLP-1 therapies like Trulicity and Victoza (liraglutide) if there is a family history of medullary cell carcinoma of the thyroid or Multiple Endocrine Neoplasia Type 2 (MEN 2)

Contractor benefits vary by company

nmcd-journal.com Track glucose proactively

Zepbound trial data in its prescribing information reported constipation in 11% to 17% of treatment groups across labeled doses

95% CI 0.66, 0.75