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CLA may increase the release or availability of fatty acids from adipose tissue while L-carnitine facilitates their mitochondrial uptake

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But the finding is the latest see-saw of scientific evidence on the risk of depression and suicide tied to the popular medications and critics say evidence that the drugs cause problems with mood is limited

This aligns with studies showing increased CD36 localization on hepatocyte membranes in MASH patients, where CD36 palmitoylation promotes free fatty acid uptake and exacerbates intracellular lipid deposition