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Neinstein explains

The day after her first IV, she reported that her brain function and energy improved from 1/10 to 3/10, and after subsequent treatments, she has fully recovered

In a six-month clinical trial, a GLP-1 drug called liraglutide was shown to slow the progression of the disease and improve the cerebral metabolic rate of glucose (CMRglc), which is a measurement of glucose metabolism in the brain important for normal cognitive function

That realization can bring grief

Among tirzepatide users across all doses, 28 patients developed urinary tract infections

While some patients hope to be an exception, relying on diet and exercise alone after stopping the medication, the fundamental biology of obesity means that the crutch metaphor often falls short