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Since adiponectin increases cellular sensitivity to insulin [37, 125,126,127] and also possesses anti-atherogenic effects [128,129,130], a marked reduction in the circulatory concentrations of adiponectin results in IR and atherosclerosis via systemic inflammation [115]

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The ResurFX device can cover a treatment area in approximately 20 minutes , but its results are long-lasting

Higher than expected free fractions occur in the elderly, in hyperlipidemic patients, and in patients with hepatic and renal diseases

doi: 7 10.1007/s00415-00017-08415-00411

With the new advancement it will be able for a faster drug release which facilitates more rapid therapeutic effect and high protection from degradation of sensitive compounds