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doi: 10.3390/ijms231911531 57 Otulak-KozieK.KozieE.LockhartB

Three phases of detoxification:[ref] Phase I (bioactivation transformation) involves breaking apart large toxins and converting them into polar molecules

It can make it harder to know which compound is helping, which one is causing side effects, and how the overall protocol should be adjusted

This reference does not suggest if a nootropic works or not -- but it does explain why it may be categorized as a nootropic, as well as serving as a starting point for additional research

p53 N-terminal phosphorylation: a defining layer of complex regulation

Around half of the infants daily energy intake stems from fat