Roesel RA, Hommes FA, Samper L: Pyroglutamic aciduria (5-oxoprolinuria) without glutathione synthetase deficiency and with decreased pyroglutamate hydrolase activity
It is derived from the C-terminal end of alpha-melanocyte-stimulating hormone, and it retains the parent molecule anti-inflammatory properties without the melanogenic (skin-darkening) effects
[PMID: 32504923 DOI: 10.1016/j.mehy.2020.109862] [DOI] [PMC free article] [PubMed] [Google Scholar] 56.Zhou N, Yang X, Huang A, Chen Z
Yes, these two supplements are highly complementary and safe to take together
It sits inside the broader category of peptide therapy we use in regenerative care, alongside compounds aimed at metabolism, hormones, and gut health
Important: Always consult with your healthcare provider before starting a new supplement routine, especially if you are pregnant, nursing, or taking medication