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[10] reported that metformin acutely and selectively increased plasma levels of GLP-1 in mice, even in the absence of concomitant oral glucose administration, while it did not increase plasma levels of the other incretin hormone, glucose-dependent insulinotropic polypeptide (GIP), or, curiously, peptide YY, a gastrointestinal hormone co-localised with GLP-1 in L cells

Monitor Your Micros: Sometimes, rapid weight loss leads to nutrient gaps

10.1038/cdd.2015.93 45 HerbetM.Natorska-ChomickaD.OstrowskaM.Gawroska-GrzywaczM.IzdebskaM.Pitkowska-ChmielI.et al (2019)

Liraglutide attenuates the osteoblastic differentiation of MC3T3-E1 cells by modulating AMPK/mTOR signaling

doi: 10.1136/jnnp.2008.157354 66

Its a prebiotic, promoting the growth of beneficial gut bacteria