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(31) In one case study, primary hypothyroidism was caused by a deficiency of amino acids while the patient was on a protein-calorie restricted diet

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Our experimental results demonstrated that the regulation of GGCT expression by Gln occurs neither at the transcriptional level nor via translational regulation, but is achieved at the post-transcriptional level by modulating the stability of GGCT mRNA

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Rapid ligand-receptor binding and efficient uptake by target cells are critical for receptor-targeted delivery systems to avoid in vivo clearance