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All the dogs were able to continue eating naturally

393 Studies indicate that a lack of SIRT6 leads to reduced mitochondrial gene expression, increased production of ROS, and accelerated mitochondrial decay, collectively triggering mitochondrial dysfunction

Science of the Total Environment, 745: 140882 Cheng Q, Liu Z, Huang Y, Li F, Nengzi L, Zhang J (2020)

And I think that's what happens with

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doi: 10.3389/fnut.2025.1627949 Received 14 May 2025 Accepted 11 July 2025 Published 30 July 2025 Volume 12 - 2025 Edited by Hariprasath Lakshmanan, JSS Academy of Higher Education and Research, India Reviewed by Marisabel Mecca, Oncological Center of Basilicata (IRCCS), Italy Mohit Agrawal, K