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Preproglucagon expressing neurons in the NTS project to many parts of the brain, including the hypothalamus, thalamus, parabrachial nucleus, parts of the mesolimbic dopamine system, raphe nucleus, amygdala, hippocampus and medial prefrontal cortex [32]

This suggests a change in the innate immune system in obesity [13]

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We're throwing all that potential data away that could be used to actually identify real safety and evidence signals

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