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Replication protein A (RPA) has demonstrated its capability in DNA damage response, as well as in HR and NER DNA repair pathways, and potential chemical candidates against RPA have been shown to increase sensitivity to anti-cancer agents

Jones SM, Boobis AR, Moore GE, Stanier PM

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Investigation of distribution of GSK-3 signal pathway by age groups in cases of ulcerative colitis

Owing to hypermethylation of the promoter, RIPK3 is silenced in primary tumours but significantly upregulated in recurrent lesions, with an enhanced dependence on cysteine metabolism, suggesting that targeting RIPK3 may inhibit tumour recurrence [56]

D., Flanagan, J