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Blood-brain-barrier spheroids as an in vitro screening platform for brain-penetrating agents

Follow-up Repeat metabolic markers after 4-12 weeks, with closer review during dose escalation or major appetite changes

[DOI] [PubMed] [Google Scholar] 2.Bacon NJ, White RAS

However, with the improvement of modern living standards, many factors such as prolonged artificial lighting, sedentarism, short sleep duration, intestinal flora and high-calorie food intake have disturbed circadian rhythm regulation on various metabolic processes, including GLP-1 secretion, which plays an essential role in the development of various metabolic diseases

Pediatrics 146 (1), e20192493