Given the lipid-rich composition of myelin, such metabolic perturbations precipitate myelin deterioration and demyelination, leading to a decrease in nerve conduction velocity (Johnson and Stolzing, 2019
Apart from the common ALA and vitamins in practice, other antioxidants, although not yet widely used, also show potential in treating neurological diseases
folic acid may improve anemia but not prevent nerve damage
These findings suggest that encapsulation enhances the bioactivity, solubility, and permeability of polyphenols by increasing their bioavailability
All of the reasoning above is based on the independent mechanisms of each peptide and the absence of known interactions between their respective pathways
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