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When To Take High-Dose Vitamin B12 Supplements Treating Vitamin B12 Deficiency People take high-dose vitamin B12 to treat a vitamin deficiency (levels below 200 to 250 pg/mL)

It's typically diagnosed through a complete blood count (CBC) and peripheral blood smear, which reveals the enlarged red blood cells

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It becomes harder to absorb vitamin B12 from food as we grow older

In fact, for every 500 g of oral B12 supplement ingested, only about 10 g is absorbed

The most alarming of these is its cancer risk