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If retatrutide is authorised, wed expect criteria similar to current NHS policies for weight-management injections: a BMI threshold (with lower thresholds for some ethnic groups), presence of weight-related conditions (e.g., hypertension, OSA, prediabetes), and use alongside structured lifestyle support

However, this area remains under-researched, highlighting the need for further studies

The Specific Endpoints Being Measured: This is a huge one

If you have a history of mental health conditions, it's important to talk to your healthcare provider before starting medications like Semaglutide or Tirzepatide

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the relevance to humans is not established, which is the basis for the boxed warning