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The level of iNOS and nNOS was below the method threshold (not presented)

doi:10.1016/S0378-1119(97)00411-3

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Clinical trial data from the NEJM Phase 2 study showed that gastrointestinal events were predominantly mild to moderate, occurred primarily during dose escalation, and were partially mitigated by starting at 2mg rather than 4mg

Research suggests they may also have applications in mood enhancement and disease prevention, though more studies are needed to confirm these findings

These are not all of the side effects that may occur