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Cowan CS, Callaghan BL, Richardson R

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Circadian disruption in beta-Bmal1(-/-) mice and arrhythmic Clock 19 mice decrease the Nrf2 expression and subsequently impair the antioxidant defense system, contributing to increased ROS accumulation, oxidative damage and mitochondrial uncoupling

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GHK-Cu activates copper-dependent collagen synthesis and antioxidant gene expression