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Knockout RAGE alleviates cardiac fibrosis through repressing endothelial-to-mesenchymal transition (EndMT) mediated by autophagy

Common signs include persistent fatigue, muscle weakness, a "pins and needles" sensation in the hands or feet, and difficulty with memory or focus

The greater reduction in body weight and HbA1c levels compared to SGLT-2i monotherapy and TAU are noteworthy, as achieving optimal glycemic control and weight management are central to diabetes management

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Men with a body mass index (BMI) above 30 show significantly lower sperm concentration and quality compared to normal-weight men, effects that often reverse with weight loss

In cases where multiple studies originated from the same cohort, the study with the larger sample size was selected