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Uterine-specific deletion of Arid1a compromises gland development, diminishes Foxa2 and Lif expression, and disrupts the LIF-STAT3-EGR1 pathway, leading to implantation failure and subfertility

PI cannot penetrate intact cell membranes and thus only stains cells whose membrane integrity is compromised, such as apoptotic or necrotic cells

J., Schofield, C

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Panel B: In a post-translational modification called 4-pantetheinylation, the enzyme 4-phosphopantetheinyl transferase catalyzes the hydrolysis of coenzyme A into 3,5-adenosine diphosphate and 4-phosphopantetheine and the transfer of the 4-phosphopantetheinyl moiety to a specific serine residue of FDH